Neurocognitive Performance Deficits Related to Immediate and Acute Blast Overpressure Exposure

Brain Vulnerability to Repeated Blast Overpressure and Polytrauma

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Integrity Disruption of an In Vitro Blood-Brain Barrier Model Following Exposure to Blast Overpressure

Traumatic brain injury (TBI) is the signature injury of modern military conflicts due to the prevalence of improvised explosive devices (IEDs). However, the pathobiology of blast-induced traumatic brain injury (bTBI) and its effects on the blood-brain barrier (BBB) – a structure essential for maintaining brain homeostasis – remain poorly understood. This work utilized a helium-driven shock tube...

Compulsivity-related neurocognitive performance deficits in gambling disorder: A systematic review and meta-analysis

Compulsivity is a core feature of addictive disorders, including gambling disorder. However, it is unclear to what extent this compulsive behavior in gambling disorder is associated with abnormal compulsivity-related neurocognitive functioning. Here, we summarize and synthesize the evidence for compulsive behavior, as assessed by compulsivity-related neurocognitive tasks, in individuals with ga...

Assessment of the Effects of Acute and Repeated Exposure to Blast Overpressure in Rodents: Toward a Greater Understanding of Blast and the Potential Ramifications for Injury in Humans Exposed to Blast

Mild traumatic brain injury (mTBI) resulting from exposure to improvised explosive devices (IEDs) has fueled a requirement to develop animals models that mirror this condition using exposure to blast overpressure (BOP). En route to developing a model of repeated exposure to BOP we sought to initially characterize the effects of acute BOP exposure in rodents, focusing specifically on the levels ...

An Analysis of the Blast Overpressure Study Data Comparing Three Exposure Criteria